[Description of an isoniazid-resistant tuberculosis outbreak in a block of apartments].
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چکیده
منابع مشابه
IMPORTANCE OF CATALASE ENZYME IN VIRULENCE OF ISONIAZID RESISTANT ST RAINS OF MYCOBACTERIUM TUBERCULOSIS IN GUINEAPIGS
In this study, twenty-five strains of Mycobacterium tuberculosis resistant to isoniazid (INH) were isolated from patients with tuberculosis (TB). Nine strains (36%) were found to be virulent in guinea-pigs [root index virulence (RIV» 1 ]. The remaining sixteen strains (64%) were non-virulent (RIV <1). Of the nine strains resistant to INH as well as virulent to guinea-pigs, eight of them wer...
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Background and Objective: Drug resistance to tuberculosis is continuously increasing and is a significant threat to tuberculosis control programs because afew effective drugs are present against Mycobacterium tuberculosis. Although isoniazid (INH) is the most effective drug against tuberculosis, resistance to this drug also develops readily. Mutations in katG, specially the Ser315Thr substituti...
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ورودعنوان ژورنال:
- Anales de pediatria
دوره 87 5 شماره
صفحات -
تاریخ انتشار 2017